Central DuPage Hospital Logo

Thomson Reuters Top 100 Hospitals CDH

Text Size Default Text Size button Medium Text Size button Large Text Size button
Share | Facebook Twitter YouTube
Clinical Trials Research: Clinical Trials Chart
<< Back to Clinical Trials Research

Clinical Trials Chart

Oncology

Study Title

Indication

Clinical
Trial
Number

Principal
Investigator

Contact  

A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) vs. Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer

Breast Cancer

B-39

C. Kesslering, MD

Claudia Fredian, RN 630-352-5361

A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation Plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer

Breast Cancer

R 1005

C. Kesslering, MD

Claudia Fredian, RN 630-352-5361

A Randomized Phase III Trial of Adjuvant Therapy ComparingChemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer

Breast Cancer

B-47

J. Ayers, MD (CDH) P. Menini, DO (Delnor)

 

Claudia Fredian, RN 630-352-5361

A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER-2-Positive Ductal Carcinoma In Situ Resected by Lympectomy

Breast Cancer

B-43

J. Ayers, MD (CDH) P. Menini, DO (Delnor) 

Claudia Fredian, RN 630-352-5361

A Randomized Double Blinded Phase III Study Comparing Gemcitabine, Cisplatin , and Bevacizumab (IND#7921) to Gemcitabine, Cisplatin and Placebo in Patients with Advanced Transitional Cell Carcinoma

Bladder Cancer

C 90601

M. Kahn, MD (CDH)
C. George, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Prospective Observational  Multicenter Cohort Study To Assess The Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients with Bone Metastasis Starting Zoledronic Acid Treatment

Bone Metastasis

S702

J. Ayers, MD (CDH) P. Menini, DO (Delnor) 

Claudia Fredian, RN 630-352-5361

A Phase III Trial of Adjuvant Chemotherapy as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: The Outback Trial

Cervical Cancer

G0274

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

A Randomized, Double-Blind, Multicenter, Phase III study of Irinotecan, Folinic Acid, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab or Placebo in Patients with metastatic Colorectal Carcinoma Progressive During or Following First-Line combination therapy

Colorectal Cancer

I4T-MC-JVBB

M. Kahn, MD
(CDH)
A.Ragam, MD (Delnor)

Claudia Fredian, RN 630-352-5361

A Phase III Trial of Pelvic Radiation Therapy vs. Vaginal Cuff Brachytherapy Followed by Paclitaxel/Carboplatin in Patients with High-Risk, Early Stage Endometrial Cancer

Endometrial Cancer

G0249

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

A Randomized Phase III Trial of Cisplatin and Tumor Volume Directed Irradiation Followed by Carboplatin & Paclitaxel vs. Carboplatin & Paclitaxel for Optimally Debulked Advanced Endometrial Carcinoma

Endometrial Cancer

G0258

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

A Phase II Study of MK-2206 (NSC-749607) as Second Line Therapy for Advanced Gastric and Gastroesophageal Junction Cancer

Gastro Esophageal
Cancer


S1005

M. Kahn, MD
(CDH)
A.Ragam, MD (Delnor)

Claudia Fredian, RN 630-352-5361

A Genetic Risk-Stratified, Randomized Phase II Study of Four Fludarabine/Antibody Combinations for Patients with Symptomatic Previously Untreated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia (CLL)

C10404

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

Studying Interventions for Managing Patients with Chronic Myeloid Leukemia in Chronic Phase: The 5 Year Prospective CohortStudy

Chronic Myeloid Leukemia (CML)

SIMPLICITY

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Randomized Controlled Study of Yondelis (trabectedin) or Dacarbazine for the Treatment of Advanced Liposarcoma or Leiomyosarcoma Previously Treated with and Anthracycline and Ifosfamide

Liposarcoma or Leiomyo-sarcoma

ET743-SAR-3007

J. Ayers, MD

Claudia Fredian, RN 630-352-5361

A Phase III Evaluation of Docetaxel and Gemcitabine Plus G-CSF with Bevacizumab Versus Docetaxel and Gemcitabine Plus G-CSF with Placebo in the Treatment of Recurrent or Advanced Leiomyosarcoma of the Uterus

Uterine Leiomyosarcoma

G250

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

A Phase III Randomized, Double Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion

Liver Cancer

E1208

M. Kahn, MD
(CDH)
C. George, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Phase III Randomized Trial of Adjuvant Chemotherapy with or without Bevacizumab for Patients with Completely Resected Stage 1B-IIIA Non-Small Cell Lung Cancer

Lung Cancer, Non-Small Cell

E1505

L. Ferris, MD
(CDH)
P. Menini, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Randomized phase III study comparing carboplatin/paclitaxel or carboplatin/paclitaxel/bevacizumab with or without concurrent cetuximab in patients with advanced non-small cell lung cancer

Lung Cancer, Non-Small Cell

S0819

L. Ferris, MD
(CDH)
P. Menini, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC

Lung Cancer, Non-Small Cell

E5508

L. Ferris, MD
(CDH)
P. Menini, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkins Lymphoma using Early Interim FDG-PET Imaging

Hodgkin’s Lymphoma

S0816

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination With Rituximab-CHOP in Patients With Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)

B-Cell Lymphoma

S806

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

Randomized phase III trial comparing the frequency of major erythroid response (MER) to treatment with Lenalidomide (Revlimid) alone and in combination with Epoetin Alfa (Procrit) in subjects with Low-or Intermediate-1 risk MDS and Symptomatic Anemia

Myleodysplastic syndrome (MDS)

E2905

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

A Prospective, Longitudinal Study (Phase II) of YKL-40 in Patients with FIGO Stage III or IV Invasive Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Undergoing Primary Chemotherapy

Ovarian, Primary Peritoneal or Fallopian Tube Cancer

G235

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

Randomized Phase III Trial of maintenance chemo comparing 12 monthly cycles of single agent Paclitaxel or CT-2103 versus no treatment until documented relapse in women with advanced ovarian primary peritoneal or fallopian tube cancer who achieve a complete clinical response to  primary platinum/taxane based chemotherapy

Ovarian, Primary Peritoneal or Fallopian Tube Cancer

G212

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

Chemotherapy Toxicity In Elderly Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Ovarian, Primary Peritoneal or Fallopian Tube Cancer

G273

B. Buttin, MD

Claudia Fredian, RN 630-352-5361

Randomized Phase III Study of Neoajuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High Risk, Clinically localized Prostate Cancer

Prostate Cancer

C90203

M. Kahn, MD
(CDH)
C. George, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

Everolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study

Renal Cancer (Kidney Cancer)

S0931

M. Kahn, MD
(CDH)
C. George, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

Pathologic review for any Hematological malignancies diagnosed at any time

Leukemias, Lymphomas

CASE 5Z08

J. Ayers, MD
(CDH)
R. Bayer, MD
(Delnor)

Claudia Fredian, RN 630-352-5361

 

Neuroscience

Study Title

Indication

Clinical
Trial
Number

Principal
Investigator

Contact  

Analysis of Cerebral Aneurysm Rupture Risk through 3D Rotational Angiography Based Mesh Generation and Computational Fluid Dynamic Simulation

Aneurysm Rupture Risk

 

R. Deveshwar, MD

Joyce Smith, RN
630-933-6107

A Double-blind, Placebo Controlled, Randomized, Multicenter Study to Assess the Safety and Clinical Benefit of Rasagiline as an Add on Therapy to Stable Dose of Dopamine Agonists in the Treatment of Early Parkinson's Disease

Parkinson’s Disease

NCT1049984

M. Rezak, MD

Pauline Pastore, RN
630-933-6107

Extended Release Amantadine Safety and Efficacy Study in Levodopa-Induced Dyskinesia (EASED Study) ADS-PAR-AM201

Parkinson’s Disease

NCT01397422

M. Rezak, MD

Pauline Pastore, RN
630-933-6107

Prospective, Observational Trial evaluating Xeomin for Cervical Dystonia or Blepharospasm in the US

Cervical Dystonia or Blepharospasm

NCT1287247

M. Rezak, MD

Pauline Pastore, RN
630-933-6107

CANOPY: Carotid Artery Stenting Outcomes in the Standard Risk Population for Carotid Endarterectomy

Stroke
Carotid Artery Stenting

NCT1445613

H. Shownkeen, MD

Joyce Smith, RN
630-933-6107

CHOICE: Carotid Stenting for High Surgicial Risk Patients: Evaluating Outcomes Through the Collection of Clinical Evidence

Stroke
Carotid Artery Stenting

NCT406055

H. Shownkeen, MD

Joyce Smith, RN
630-933-6107

Saphhire World Wide Study:  Stenting & Angioplasty with protection in patients @ high risk for Endarterectomy Registry using Enterprise HUD

Stroke
Carotid Artery Stenting

NCT403078

H. Shownkeen, MD

Joyce Smith, RN
630-933-6107

The THERAPY Trial: the Randomized, Concurrent Controlled Trial to Assess the Penumbra System's Safety and Effectiveness in the Treatment of Acute Stroke

Stroke

NCT1429350

H. Shownkeen, MD

Joyce Smith, RN
630-933-6107

Trevo 2: Thrombectomy Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke

Stroke

NCT1088672

H. Shownkeen, MD

Joyce Smith, RN
630-933-6107

A randomized double blind placebo controlled multicenter parallel group study to evaluate the efficacy and safety of brivaracetam in subjects (16 to 80 years old) with partial onset seizures 1358

Epilepsy

NCT1261325

R. Sucholeiki, MD

Kimberly Woodson, RN
630-933-6844

Double-Blind, Randomized, Historical Control Study of the Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects with Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs

Epilepsy

NCT866775

R. Sucholeiki, MD

Kimberly Woodson, RN
630-933-6844

Long-Term Eslicarbazepine Acetate Extension Study

Epilepsy

NCT910247

R. Sucholeiki, MD

Kimberly Woodson, RN
630-933-6844

Open Label multicenter follow up study to evaluate the long term safety and efficacy of brivaracetam used as an adjunctive treatment in subjects aged 16 or older with partial onset seizures

Epilepsy

NCT1339559

R. Sucholeiki, MD

Kimberly Woodson, RN
630-933-6844